| Highways |
Monterrey is the hub in a broad network of highways, including the modern toll highways to Nuevo Laredo and Reynosa. Total road network: 4,500 mi (7,245 km)Toll roads: 204 mi (329 km)
Free roads: 2,450 mi (3,942 km) | 
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| Federal highways |
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| Main highways |
| No. 40 | Matamoros - Mazatlán highway |
| Crosses Nuevo León from east to west |
Reynosa, Tamaulipas  Monterrey, Nuevo León Saltillo, Coahuila North, Northeast and Center of Mexico |
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| No. 85 | Mexico City – Laredo (Federal highway) |
| Crosses Nuevo León from southeast to north |
| Southeast and Gulf of Mexico Cd. Victoria, Tamaulipas Monterrey, Nuevo León Nuevo Laredo, Tamaulipas |
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| Others |
| No. 53 | Monclova, Coahuila Monterrey, Nuevo León |
| No. 54 | Miguel Alemán, Tamaulipas Monterrey, Nuevo León |
| No. 57 | Matehuala, San Luis Potosí South of Nuevo León Monterrey, Nuevo León |
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| State highways |
| No. 1 | Colombia, Anáhuac, Nuevo León Monterrey, Nuevo León |
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Bus Station
Cristóbal Colón, Col. Madero, C.P. 64000
Monterrey, Nuevo León
Ph: (81) 8372 9324
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| Bus companies operating in Monterrey: |
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| Distances in miles (km) to: |
| Saltillo, Coahuila | 51 (82) |
| Reynosa, Tamaulipas | 137 (220) |
| McAllen, Texas, USA | 137 (220) |
| Nuevo Laredo, Tamaulipas | 139 (224) |
| Laredo, Texas, USA | 139 (224) |
| Piedras Negras, Coahuila | 256 (412) |
| Zacatecas, Zacatecas | 301 (485) |
| Tampico, Tamaulipas | 337 (543) |
| San Luis Potosí, San Luis Potosí | 339 (546) |
| Durango, Durango | 347 (558) |
| Aguascalientes, Aguascalientes | 373 (601) |
| León, Guanajuato | 462 (744) |
| Querétaro, Querétaro | 466 (750) |
| Guadalajara, Jalisco | 498 (802) |
| Chihuahua, Chihuahua | 508 (818) |
| Mazatlán, Sinaloa | 577 (928) |
| México City | 595 (957) |
| Veracruz, Veracruz | 644 (1036) |
| Puebla, Puebla | 692 (1114) |
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